top of page

Resources & Outputs

Inno4vac has developed open-source biological and mathematical models that predict vaccine performance and bio-manufacturing outcomes, freely available to support researchers and R&D developers worldwide.

overview of models.png

Inno4vac Subtopic 3 (ST3)  - State-of-art innovations in human in vitro 3D mucosa models and assays  - developed cell-based human in vitro 3D models that simulate an infection at the mucosa and more reliably predict immune protection, namely gastrointestinal mucosa, respiratory mucosa and urovaginal  mucosa. 

 

These models can be combined with the development of related functional immune assays for clinically relevant (surrogate) endpoints. 

Button

Air-liquid interface HSV2

Infection(s):

Developer:

HSV2

Julius-Maximilians-Universität Würzburg

Button

Air-liquid interface for N. gonorrhoea

Infection(s):

Developer:

N. gonorrhoea

Julius-Maximilians-Universität Würzburg

Button

Gut organoid for Norovirus

Infection(s):

Developer:

Norovirus

University of Nottingham

Button

Lung organoid for Influenza

Infection(s):

Developer:

Influenza

University of Bergen

Button

Lung-on-chip for RSV

Infection(s):

Developer:

RSV

Jena University Hospital

Button

UV-on-chip for HSV2

Infection(s):

Developer:

HSV2

Eberhard Karls University Tübingen

Button

Air-liquid interface for C. trachomatis  

Infection(s):

Developer:

C. trachomatis

Julius-Maximilians-Universität Würzburg

Button

Air-liquid interface for RSV

Infection(s):

Developer:

RSV

Rijksinstituut voor Volksgezondheid en Milieu

Button

Gut-on-chip for C. difficile

Infection(s):

Developer:

C. difficile

Jena University Hospital

Button

Lung organoid for Influenza

Infection(s):

Developer:

Influenza

University Medical Center Groningen

Button

Nasal organoid for Influenza 

Infection(s):

Developer:

Influenza

Leiden University Medical Center

Button

Air-liquid interface for Influenza

Infection(s):

Developer:

Influenza

Rijksinstituut voor Volksgezondheid en Milieu

Button

Gut organoid for C. difficile

Infection(s):

Developer:

C. difficile

University of Nottingham

Button

Gut-on-chip for Norovirus

Infection(s):

Developer:

Norovirus

Jena University Hospital

Button

Lung-on-chip for Influenza

Infection(s):

Developer:

Influenza

Jena University Hospital

Button

Nasal organoid for RSV

Infection(s):

Developer:

RSV

Leiden University Medical Center

Overview of Mucosal Models

Inno4vac_overview Respiratory Mucosa Models.png
Inno4vac_overview gastro intestinal Mucosa Models.png
Inno4vac_overview urogenital Mucosa Models.png
bottom of page